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. 2014 Jun 3;4(6):e395. doi: 10.1038/tp.2014.39

Figure 3.

Figure 3

The effects of local application of ketamine and Ro25-6981 on glutamate clearance (T80). The elapsed time from the peak of the evoked glutamate until 80% of the response decayed (T80) was not significantly altered after local application of either ketamine (a) or Ro25-6981 (b) in any of the regions analyzed as compared with vehicle. Data represent mean±s.e.m. from five glutamate peaks from 8–14 animals. Vehicle (70 mM KCl); Ketamine (100 μM ketamine in 70 mM KCl); Ro-256981 (100 μM Ro25-6981 in 70 mM KCl). CA1, cornu ammonis 1; DG, dentate gyrus; SUB, subiculum; PreL, prelimbic region of the prefrontal cortex; IL, infralimbic region of the prefrontal cortex.