Table 2. Estimated models and model selection procedure.
Estimated model (fixed effects) | AIC |
---|---|
Model 1: Time × FKBP5 rs1360780 Genotypea | 789.52 |
Model 2: Time × FKBP5 rs1360780 T allele carrierb | 783.82 |
Model 3: Time × FKBP5 rs1360780 T allele carrier + traumatic load | 771.18 |
Model 4: Time × FKBP5 rs1360780 T allele carrier × traumatic load | 773.54 |
Model 5: Time × FKBP5 rs1360780 T allele carrier + traumatic load + sexc | 767.38 |
Model 6: Time × FKBP5 rs1360780 T allele carrier + traumatic load + sex + age | 769.23 |
Abbreviations: AIC, Akaike's Information Criterion; FKB5, FK506-binding protein 51.
The genotype model contrasts the three genotype groups (C/C, C/T and T/T).
The T allele carrier model compares carriers of the T risk allele (C/T and T/T genotypes) with non-carriers (C/C genotype).
Model 5 (marked in bold letters) was chosen based on the model selection criteria as it yielded the smallest AIC.