Table 2. Formate and methanol kinetics in 11 patients treated on IHD.
| Patient | Methanol t ½, h | R2 methanol | Formate t ½, h | R2 formate | Observation time during HD, h | Blood FR, ml/min | Dialysate FR, ml/min | Dialyzer type | Dialyzer surface area, m2 | Anticoagulation | Dialysate temperature | Number of data points | Rebound after HD |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 3.4 | 0.95 | 2.4 | 0.81 | 11.0 | 250 | 500 | Fresenius 4008S | 1.5 | Hep | 37.0 | 4 | No |
| 2 | 2.0 | 0.80 | 1.6 | 0.85 | 8.0 | 250 | 500 | Fresenius 4008S | 1.6 | Hep | 37.0 | 3 | No |
| 3 | 3.1 | 0.94 | 1.9 | 0.90 | 8.0 | 220 | 500 | Fresenius 4008S | 1.6 | Hep | 36.5 | 3 | No |
| 4 | 3.2 | 0.84 | 1.3 | 0.99 | 8.0 | 250 | 500 | Fresenius 4008S | 1.6 | Hep | 36.5 | 4 | No |
| 5 | 8.0 | 0.87 | 2.3 | 1.00 | 1.9 | 200 | 500 | Fresenius 4008S | 1.5 | Hep | 36.5 | 3 | No |
| 6 | 2.0 | 0.92 | 0.7 | 1.00 | 4.0 | 250 | 500 | Fresenius 4008S | 1.6 | Hep | 37.0 | 3 | No |
| 7 | 4.2 | 1.00 | 1.4 | 1.00 | 12.0 | 180 | 500 | Fresenius 4008S | 1.5 | Hep | 36.5 | 3 | No |
| 8 | 2.1 | 0.84 | 1.2 | 1.00 | 8.0 | 250 | 500 | Fresenius 4008S | 1.6 | Hep | 36.5 | 3 | No |
| 9 | 1.8 | 1.00 | 1.0 | 1.00 | 8.0 | 250 | 500 | Fresenius 4008S | 1.6 | Hep | 36.5 | 3 | No |
| 10 | 4.8 | 0.97 | 2.3 | 0.99 | 10.0 | 180 | 500 | Fresenius 4008S | 1.6 | Hep | 36.5 | 3 | No |
| 11 | 6.8 | 0.89 | 1.7 | 1.00 | 13.0 | 220 | 500 | Fresenius 4008S | 1.5 | Hep | 36.5 | 3 | No |
| Mean | 3.7 | 0.91 | 1.6 | 0.96 | 9.9 | ||||||||
| LCL95% | 2.3 | 1.2 | 7.3 | ||||||||||
| UCL95% | 5.1 | 2.0 | 12.5 |
Abbreviations: FR, flow rate; HD, hemodialysis; Hep, heparin; IHD, intermittent hemodialysis; LCL, the lower limit of a confidence interval at the 95% level; UCL, the upper limit of a confidence interval at the 95% level. Polysulfone dialyzer membranes have been used in all cases.