Table 1. FE of Na+ and K+ and GFR measured in control X-NDI mice (CTR) and in animals after the combined treatment with SEC and FLU (SCT+FLU).
| CTR | SCT+FLU | |
|---|---|---|
| FENa% | 0.7933±0.05812 | 0.2333±0.03528** |
| FEK% | 34.20±1.562 | 17.60±1.058*** |
| GFR (μl/min) | 218.3±9.280 | 317.3±14.89** |
Abbreviations: FE, fractional excretion; FLU, fluvastatin; GFR, glomerular filtration rate; SCT, secretin; X-NDI, X-linked nephrogenic diabetes insipidus.
**P<0.05; ***P<0.001.