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. Author manuscript; available in PMC: 2015 Apr 9.
Published in final edited form as: Chem Rev. 2014 Jan 28;114(7):3963–4038. doi: 10.1021/cr400443z

Figure 25.

Figure 25

Substrate orientation in the active site of xanthine oxidase. Left, 2-hydroxy-6-methylpurine, a poor substrate (3B9J); center, lumazine, a good substrate (3ETR); and right, xanthine (3EUB).