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. 1996 Jun;49(3):M180–M181. doi: 10.1136/mp.49.3.m180

Postmortem diagnosis of Factor V Leiden from paraffin wax embedded tissue

J S Webb 1,2, G R Standen 1,2, C M P Collins 1,2, C P Case 1,2
PMCID: PMC408048  PMID: 16696070

Abstract

Activated protein C resistance resulting from Factor V Leiden is an important inherited thrombophilia disorder which is found in 3.5% of people in the UK. The genetic defect can be detected using the PCR and the diagnosis can be made postmortem from paraffin wax embedded tissue. The presence of Factor V Leiden should be sought in all cases of unexplained sudden death resulting from venous thromboembolism.

Keywords: Factor V Leiden

Keywords: thromboembolism

Keywords: thrombophilia disorder

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Selected References

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