Table 2.
Age-specific fever episodes and incidence of dengue infection and illness in children, Sri Lanka*
Age (years) | No. children | Fever episodes | New dengue infections | Incidence of infection per 100 children | Incidence of disease per 100 children | |||
---|---|---|---|---|---|---|---|---|
Total | Mean/child | Total | Inapparent | Apparent | ||||
< 1 | 51 | 31 | 0.6 | 1 | 0 | 1 | 1.96 (0.05–10.45) | 1.96 (0.05–10.45) |
1–3 | 196 | 252 | 1.3 | 27 | 15 | 12 | 13.78 (9.28–19.41) | 6.12 (3.20–10.45) |
4–6 | 191 | 174 | 0.9 | 13 | 11 | 2 | 6.81 (3.67–11.36) | 1.05 (0.13–3.73) |
7–9 | 225 | 137 | 0.6 | 15 | 6 | 9 | 6.67 (3.78–10.76) | 4.00 (1.85–7.46) |
10–12 | 136 | 87 | 0.6 | 11 | 8 | 3 | 8.09 (3.25–16.03) | 2.21 (0.46–6.31) |
Total | 799 | 681 | 0.9 | 67 | 40 | 27 | 8.39 (6.56–10.53) | 3.38 (2.24–4.88) |
Values in parentheses are 95% confidence intervals. Clinically apparent dengue infections were diagnosed by performing paired serologic analysis and polymerase chain reaction on acute-phase and convalescent-phase serum samples obtained from febrile children. Total dengue infections over the study year were detected by testing paired baseline and end of year samples by IgG enzyme-linked immunosorbent assay and neutralization test. Children who were infected but not identified as having apparent cases were designated as having inapparent cases.