Fig. 2.

Comparison of rOv-ASP-1 and alum in inducing influenza-specific antibody responses after primary immunization with influenza vaccine. B6 mice were vaccinated with 0.3 μg of TIV alone or TIV combined with 20 μg rOv-ASP-1 or 1.2 mg alum. Titers of influenza-specific antibodies (IgG, IgG1, and IgG2c) in plasma at week 2 after immunization were determined by ELISA using TIV as antigen. Data is the combination of up to 6–12 mice/group from 2 to 3 independent experiments with similar results. ^*p < 0.05.