Skip to main content
. Author manuscript; available in PMC: 2014 Jul 3.
Published in final edited form as: Nanotoxicology. 2012 Nov 14;8(1):17–27. doi: 10.3109/17435390.2012.744110

Figure 5.

Figure 5

Pulmonary function at 24 h and 28 days post exposure to HN-MWCNT. Pulmonary function was assessed as a function of increasing methacholine dose in live mice at 24 h or 28 days after exposure to HN-MWCNT (A and B). Transpulmonary resistance (Medzhitov R) was assessed after anaesthetisation and tracheostomy (n = 6 for HN-MWCNT, n = 5 for vehicle (PBS) control). Two-factor ANOVA and Tukey post-hoc statistical analysis were performed to test for statistical significance of the effects of exposure to HN-MWCNT between WT and IL-1R−/− and between each of the vehicle controls. *p < 0.05 (C and D).