Table 5.
The genotype distribution of 5-HTTLPR and rs25531 gene polymorphism between TN patients stratified by treatment response
| Genotype | Treatment without improvement | Treatment with improvement | Adjusted OR | 95% CI | Adjusted P | ||||
|---|---|---|---|---|---|---|---|---|---|
|
5-HTTLPR |
Long-long |
15 |
19.74% |
46 |
32.62% |
1.000 |
|
|
|
| |
Long-short |
39 |
51.32% |
72 |
51.06% |
1.661 |
0.824 |
3.349 |
0.154 |
| |
Short-short |
22 |
28.95% |
23 |
16.31% |
2.933 |
1.285 |
6.696 |
0.009 |
| |
Long |
69 |
45.39% |
164 |
58.16% |
1.000 |
|
|
|
| |
short |
83 |
54.61% |
118 |
41.84% |
1.672 |
1.124 |
2.488 |
0.011 |
| rs25531 |
AA |
13 |
17.11% |
31 |
21.99% |
1.000 |
|
|
|
| |
AG |
45 |
59.21% |
76 |
53.90% |
1.412 |
0.670 |
2.975 |
0.363 |
| |
GG |
18 |
23.68% |
34 |
24.11% |
1.262 |
0.532 |
2.994 |
0.597 |
| |
A |
71 |
46.71% |
138 |
48.94% |
1.000 |
|
|
|
| G | 81 | 53.29% | 144 | 51.06% | 1.093 | 0.737 | 1.623 | 0.851 | |