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. 2014 Jun 25;15:98. doi: 10.1186/1471-2369-15-98

Table 3.

Salivary phosphorus, serum calcium, serum Ca x P, serum iPHT, serum whole PTH and iFGF23 levels at baseline and week 3

Parameter Period HS219
Placebo
Mean difference a 95% CI U test
n Mean ± SD n Mean ± SD
Serum phosphorus (mg/dl)
Baseline
35
6.7 ± 1.0
28
6.5 ± 1.3
0.2
-0.5 ~ 0.8
P = 0.677
Week 3
32
6.4 ± 1.4
28
6.3 ± 1.3
0.1
-0.6 ~ 0.8
P = 0.900
Salivary phosphorus (mg/dl)
Baseline
35
24.0 ± 10.4
28
23.7 ± 8.9
0.2
-4.6 ~ 5.1
P = 0.964
Week 3
32
22.3 ± 8.0
28
21.5 ± 9.0
0.8
-3.6 ~ 5.2
P = 0.656
Serum Ca (mg/dl)
Baseline
35
9.3 ± 0.7
28
9.2 ± 0.6
0.2
-0.1 ~ 0.5
P = 0.299
Week 3
33
9.4 ± 0.7
28
9.1 ± 0.6
0.2
-0.1 ~ 0.6
P = 0.149
Serum Ca x P (mg2/dl2)
Baseline
35
62.0 ± 10.3
28
59.3 ± 11.1
2.7
-2.8 ~ 8.2
P = 0.490
Week 3
33
59.9 ± 13.9
28
57.2 ± 11.3
2.7
-3.8 ~ 9.1
P = 0.520
iPTH (pg/ml)
Baseline
35
233 ± 148
28
233 ± 156
1
-77 ~ 78
P = 0.760
Week 3
33
207 ± 141
28
251 ± 184
-45
-130 ~ 41
P = 0.511
whole PTH (pg/ml)
Baseline
35
133 ± 89
28
137 ± 97
-4
-51 ~ 44
P = 0.899
Week 3
33
118 ± 92
28
140 ± 102
-22
-72 ~ 28
P = 0.511
iFGF23 (log10 pg/ml) Baseline
35
4.1 ± 0.5
28
4.0 ± 0.6
0.1
-0.2 ~ 0.3
P = 0.736
Week 3 33 4.0 ± 0.5 28 4.0 ± 0.5 0.0 -0.3 ~ 0.3 P = 0.960

aMean difference between HS219 and placebo of group at baseline or week 3.