Table 1.
Probabilities of the proband having genotype k (defined as the number of non-reference alleles), given the parental genotype (left column) and depending on whether the locus under consideration is in an IBD or NIBD region
genotype pairs | IBD | NIBD | ||||||
---|---|---|---|---|---|---|---|---|
k | k | |||||||
(i, j) | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 |
(0, 0) | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
(0, 1) | 1/2 | 1/2 | 0 | 0 | 1/2 | 1/2 | 0 | 0 |
(0, 2) | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
(1, 0) | 1/2 | 0 | 1/2 | 0 | 0 | 1 | 0 | 0 |
(1, 1) | 1/4 | 1/4 | 1/4 | 1/4 | 0 | 1/2 | 1/2 | 0 |
(1, 2) | 0 | 1/2 | 0 | 1/2 | 0 | 0 | 1 | 0 |
(2, 0) | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
(2, 1) | 0 | 0 | 1/2 | 1/2 | 0 | 0 | 1/2 | 1/2 |
(2, 2) | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
(i, j) represents ordered genotype pairs for NDJP and the other parent, respectively.