Table 1.
Baseline demographic variables, disease features, and laboratory findings in patients with Crohn’s disease (CD) selected for color Doppler ultrasound evaluations of CD lesions in the small intestine
| Demography | “Hypo-flow” | “Hyper-flow” | p value |
|---|---|---|---|
| |
(n = 4) |
(n = 8) |
|
| Age in years |
40.0 ± 8.2 |
26.8 ± 13.8 |
0.1111) |
| Male (%) |
2 (50.0) |
3 (37.5) |
1.0002) |
| CD duration in years |
13.8 ± 7.8 |
3.9 ± 4.2 |
0.0811) |
| Previous segmental resection, % |
0 |
0 |
|
| Disease location, n (%)* |
|
|
0.4912) |
| L1 (distal 1/3 ileum ± limited cecal) |
0 (0.0) |
3 (37.5) |
|
| L3 (ileocolonic) |
4 (100.0) |
5 (62.5) |
|
| L4b (upper, distal to ligament of Treitz and proximal to distal 1/3 ileum) |
0 (0.0) |
0 (0.0) |
|
| Disease behavior, n (%)* |
|
|
|
| B1 (nonstricturing, nonpenetrating) |
0 (0.0) |
0 (0.0) |
|
| B2 (stricturing) |
4 (100.0) |
8 (100.0) |
|
| B3 (penetrating) |
0 (0.0) |
0 (0.0) |
|
| B4 (structuring and penetrating) |
0 (0.0) |
0 (0.0) |
|
| Primary indication for surgery, n (%) |
|
|
1.0002) |
| Recurrence of obstruction symptoms |
4 (100.0) |
7 (87.5) |
|
| Intractable disease |
0 (0.0) |
1 (12.5) |
|
| CDAI |
196.2 ± 73.8 |
198.2 ± 63.9 |
0.9631) |
| C reactive protein (mg/dl) |
1.30 ± 2.01 |
0.47 ± 0.34 |
0.4661) |
| Erythorocyte sedimentation rate (mm/h) |
32.0 ± 30.0 |
16.9 ± 14.3 |
0.2511) |
| Preoperative therapy, n (%) |
|
|
|
| 5ASA |
4 (100.0) |
5 (62.5) |
0.4912) |
| Elemental diet (>900 kcal) |
4 (100.0) |
7 (87.5) |
1.0002) |
| TPN |
2 (50.0) |
3 (37.5) |
1.0002) |
| CS (prednisolone) |
0 (0.0) |
4 (50.0) |
0.2082) |
| AZA/6MP |
0 (0.0) |
4 (50.0) |
0.2082) |
| Anti-TNF-α biologics |
1 (25.0) |
0 (0.0) |
0.3332) |
| Antibiotics | 2 (50.0) | 3 (37.5) | 1.0002) |
1)Student’s t-test; 2)Fisher’s exact test; *Paris classification of CD; CDAI, Crohn’s disease activity index (≥150 indicates active disease); 5ASA, 5-aminosalycilic acid; 6MP, 6-mercaptopurine; AZA, azathioprine; TPN, total parenteral nutrition.