Table 2.

SNPs significantly associated with unidirectional allele specific expression in human bone samples

Gene	SNPa	Sample ID	Gender	Age	Race	T-test	Allele 1b	Allele 2	Relative Expression of Allele 1	Relative Expression of Allele 2	Ratio of expression Allele 2/Allele 1
IBSP	rs17013181	ASE-50	Male	51	European-American	2.61E-03	A	G	0.52	0.48	−1.10
		ASE-39	Male	55	European-American	2.49E-03	A	G	0.52	0.48	−1.10
		ASE-9	Male	62	European-American	2.38E-03	A	G	0.52	0.48	−1.10
		ASE-25	Male	63	European-American	1.02E-02	A	G	0.52	0.48	−1.10
		ASE-30	Male	64	European-American	1.82E-07	A	G	0.55	0.45	−1.21
		ASE-31	Male	68	European-American	1.56E-09	A	G	0.52	0.48	−1.10
		ASE-41	Male	74	European-American	1.56E-08	A	G	0.54	0.46	−1.19
		ASE-36	Male	77	European-American	3.30E-06	A	G	0.54	0.46	−1.19
		ASE-22	Female	40	European-American	6.80E-05	A	G	0.53	0.47	−1.15
		ASE-38	Female	56	European-American	5.76E-08	A	G	0.56	0.44	−1.28
		ASE-17	Female	57	European-American	6.74E-06	A	G	0.53	0.47	−1.15
		ASE-32	Female	59	European-American	2.04E-10	A	G	0.56	0.44	−1.26
		ASE-2	Female	69	European-American	1.83E-05	A	G	0.55	0.45	−1.20
		ASE-24	Female	69	European-American	2.01E-03	A	G	0.52	0.48	−1.08
		ASE-8	Female	83	European-American	5.03E-08	A	G	0.55	0.45	−1.21
		ASE-40	Female	77	African-American	2.39E-10	A	G	0.55	0.45	−1.20
		ASE-43	Female	77	African-American	4.62E-04	A	G	0.53	0.47	−1.15
		ASE-52	Female	80	African-American	1.50E-02	A	G	0.52	0.48	−1.07
SPP1	rs6812524	ASE-40	Female	77	African-American	7.60E-07	G	A	0.48	0.52	1.07
		ASE-43	Female	77	African-American	9.50E-05	G	A	0.49	0.51	1.06
		ASE-52	Female	80	African-American	1.2E-09	G	A	0.47	0.53	1.13

^aChromosome positon, MAF and Function of SNPs rs1701381 (88,732,763; 0.265; Missense) and rs6812524 (88,902,725; 0.063; Synonymous)

^bBold represents reference allele

MAF: Minor allele frequency base d on dbSNP database (http://www.ncbi.nih.gov/SNP/; Build 137)