Figure 10.
Structural location of human and macaque interspecies sequence diversity and macaque polymorphism of FcγRIIa. The locations of polymorphic or non-polymorphic amino acids are shown on the alpha carbon trace of residues 4 -170 of human FcγRIIa. Cyan spheres show the location of non-polymorphic amino acids that are identical to both M. nemestrina (A) and M. mulatta (B) but differ from human FcγRIIa. The red spheres indicate the location of residues where polymorphism is unique to one macaque species. The yellow spheres indicate location of residues where polymorphism has been identified in both M. nemestrina and M. mulatta. Sequence numbering follows that of Fig. 1.