Mouse epidermal JB6 (A), human epidermal HaCaT cells (B), and NHEK (C) were seeded and grown overnight in 96 well plates. These cells were then exposed to either DMSO alone (VC), 50 μM AEOL 10150 alone (AEOL), 0.25 mM CEES in DMSO (CEES), or to 50 μM AEOL 10150 1 h after 0.25 mM CEES exposure (CEES+AEOL) for 48 h. Thereafter, MTT assay was carried out as described under Materials and Methods. Data shown are mean ± SEM of 4-6 independent samples for each treatment. *, p<0.05 as compared to CEES exposed group.