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Comparison of Rab6 in mammalian cells and Ypt6 in yeast S. cerevisiae
| Rab/Ypt | Isoform | Localization | Transport step | Homologous effector |
|---|---|---|---|---|
| Rab6 | Rab6A, Rab6A′, Rab6B, Rab6Ca | Golgi | Endosome-to-Golgi, Golgi-to-ERb, intra Golgi | TMF/ARA160 |
| Ypt6 | Ypt6 | Golgi | Endosome-to-Golgi, intra Golgi | Sgm1 |
aRab6C predominantly localizes to centrosomes and is associated with regulation of cell cycle progression
bUnlike Rab6A and Rab6A′, Rab6B is only associated with Golgi-to-ER trafficking
