Table 2.

Experimental conditions and outcomes

Model	Disease state	Diet/treatment	ANA	Renal disease	Atherosclerosis.
MRL-lpr – ‘mild’ 1	Early	NC/Rosi.	↓	↓	n/a
gld.apoE−/−1	Early	NC/Rosi.	↓	↓	↓
MRL-lpr – ‘mild’	Early	NC/Pio.	↓	↓	n/a
MRL-lpr – ‘mild’	Established	NC/Rosi.	No change	No change	n/a
MRL-lpr – ‘severe’	Severe	NC/Rosi.	No change	No change	n/a
gld.apoE−/−	Established	NC/Rosi.	No change	No change	↓
gld.apoE−/−	Severe	WD/Rosi.	No change	↓	↓

ANA, anti-nuclear antibodies; NC, Normal chow; WD, Western diet.

¹⁸.