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Matrix-assisted laser-desorption time of flight mass spectrometry (MALDI-TOF MS) analysis of serum polyclonal IgG4κ, IgG4λ and IgG4κ/λ. Immunoglobulins were analysed native and intact (a) or following reduction with 10 mm dithiothreitol (DTT), (b). The proteins were analysed by MALDI-TOF-MS using a Bruker Ultraflextreme instrument in linear mode and using sinapinic acid as the matrix. These figures are representative for all the different IgG4 pools.
