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. 2014 Jun 10;171(13):3196–3211. doi: 10.1111/bph.12661

Figure 6.

Figure 6

hMOF regulates drug resistance and cell proliferation in human lung cancer cells. (A–C) hMOF knockdown enhances drug-induced decrease of survival. Human lung cancer A549 cells were transfected with NC-siRNA or hMOF-siRNA for 24 h. Then the cells were treated with CDDP (A), 5-FU (B) or Bleomycin (C) of the indicated concentration for 48 h. Cell survival was monitored by MTT method. (D) hMOF knockdown decreases cell proliferation. A549 cells were transfected with NC-siRNA or hMOF-siRNA. Cell proliferation was monitored by MTT method at the indicated time points post-transfection. *P < 0.05, **P < 0.01; significantly different from Ctrl.