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Comparison of the folding efficiency (i.e. fraction of proteins folded) as a function of the binding rate between BiP and unfolded proteins. In this scenario, there is no cooperative effect among chaperones in folding, unfolding, or disaggregating proteins. The model number refers to the number of binding sites. In this scenario, Model 1 has the highest folding efficiency, followed by Models 2, 3 and 4.
