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. 2014 May 15;42(12):7981–7996. doi: 10.1093/nar/gku424

Table 2.

Structural features of miRNA stem-loops from KSHV pri-miR-K10/12

graphic file with name gku424tbl1.jpg

For each KSHV miRNA stem-loop, the absence (N) or presence (Y) of positive structural criteria for Drosha/DGCR8 recognition and cleavage were determined. miRNA stem-loops were ranked in decreasing order of present determinant, defining two main groups (optimal and suboptimal) separated by a dotted line. Numbers in brackets indicate the length of the terminal loop (in nt) and of the basal stem (in bp). Stem-loops giving rise to abundant mature miRNAs in infected BCBL-1 cells are highlighted in gray.

aThe basal stem can be paired at one (+/−, value of 0.5) or both extremities (Y), forming stable platforms.

bOnly presence of a U at position -14 (+/−, value of 0.5).