Fig. 5.

Decreased Apolipoprotein B (ApoB) levels in livers of Smp30^Y/−Sod1^−/− male mice. (A) Western blot analysis of ApoB100, ApoB48, microsomal triglyceride transfer protein (MTP), and glucose-regulated protein 78 kDa (Grp78) in liver microsome fractions from each experimental group of mice. (B) Apob gene expression levels in the liver. mRNA for the Apob gene was measured using quantitative real-time polymerase chain reaction and normalized to Rplp2, ribosomal protein, large P2, and the value was expressed as arbitrary unit. The values from Smp30^Y/+Sod1^+/+ male mice were assigned a relative value of 1.0. Values are given as means ± SEM of five animals.