Table 1.
Smp30Y/+Sod1+/+ | Smp30Y/+Sod1+/− | Smp30Y/+Sod1−/− | Smp30Y/−Sod1+/+ | Smp30Y/−Sod1+/− | Smp30Y/−Sod1−/− | |
---|---|---|---|---|---|---|
Triglyceride (mg/dL) | 35.8 ± 5.4 | 33.2 ± 8.9 | 43.0 ± 5.9 | 41.5 ± 2.7 | 34.0 ± 7.0 | 84.0 ± 10.0†,§,¶,††,§§ |
Cholesterol (mg/dL) | 104.5 ± 5.7 | 122.2 ± 8.0 | 124.7 ± 11.5 | 119.7 ± 3.4 | 119.9 ± 4.1 | 116.4 ± 10.8 |
Free fatty acid (mEq/L) | 0.51 ± 0.13 | 0.75 ± 0.31 | 0.92 ± 0.21 | 0.80 ± 0.04 | 0.69 ± 0.08 | 0.84 ± 0.15 |
Aspartate aminotransferase (IU/L) | 61.7 ± 4.6 | 58.6 ± 0.9 | 66.3 ± 4.2 | 55.2 ± 3.0 | 64.6 ± 11.2 | 135.9 ± 13.8†,§,||,‡‡,§§ |
Alanine aminotransferase (IU/L) | 19.5 ± 0.9 | 21.8 ± 1.0 | 19.0 ± 0.5 | 16.4 ± 0.4‡ | 19.0 ± 1.9 | 22.3 ± 0.7∗∗ |
Glucose (mg/dL) | 163.6 ± 10.2 | 153.6 ± 8.1 | 181.0 ± 16.7 | 164.1 ± 9.0 | 147.5 ± 5.2 | 115.0 ± 7.0∗,||,∗∗ |
Insulin (ng/mL) | 0.15 ± 0.07 | 0.34 ± 0.11 | 0.06 ± 0.04 | 0.34 ± 0.02 | 0.16 ± 0.05 | 0.15 ± 0.05 |
∗p < 0.05 and †p < 0.001 versus Smp30Y/+Sod1+/+, ‡p < 0.01 and §p < 0.001 versus Smp30Y/+Sod1+/−, ¶p < 0.01 and ||p < 0.001 versus Smp30Y/+Sod1−/−, ∗∗p < 0.05, ††p < 0.01, and ‡‡p < 0.001 versus Smp30Y/−Sod1+/+, §§p < 0.001 versus Smp30Y/−Sod1+/−. Values are given as means ± SEM of animals (n = 5–10).