Table 2.
Biomarkers | Q1 | Q2 | Q3 | Q4 | p |
---|---|---|---|---|---|
Leptin, ng/mL | 4941 ± 4686 | 5471 ± 5142 | 7124 ± 7977 | 4037 ± 4592 | 0.41 |
Insulin, µUI/mL | 11.36 ± 8.6 | 10.28 ± 10.1 | 9.83 ± 5.1 | 7.80 ± 6.5 | 0.06 |
Glucose, mg/dL | 117 ± 42 | 118 ± 59 | 116 ± 91 | 110 ± 42 | 0.67 |
HbA1c, % | 7.1 ± 1.7 | 6.6 ± 1.5 | 6.4 ± 1.12 | 6.4 ± 1.43 | 0.25 |
HOMA index | 3.35 ± 3.13 | 2.92 ± 3.15 | 3.04 ± 3.31 | 2.23 ± 2.17 | 0.20 |
Total cholesterol, mg/dL | 182 ± 43 | 170 ± 37 | 190 ± 42 | 191 ± 53 | 0.32 |
LDL-cholesterol, mg/dL | 107 ± 31 | 104 ± 33 | 122 ± 40 | 116 ± 40 | 0.31 |
HDL-cholesterol, mg/dL | 34 ± 6 | 34 ± 6 | 41 ± 8 | 43 ± 11 | 0.0001 |
Triglycerides, mg/dL | 221 ± 130 | 174 ± 127 | 137 ± 57 | 149 ± 88 | 0.03 |
CKMB mass, ng/mL | 12.9 ± 27.4 | 107.9 ± 394 | 20.8 ± 45.3 | 27.1 ± 62.3 | 0.62 |
TnI, ng/mL | 6.44 ± 12.8 | 36 ± 99 | 9.44 ± 17 | 13.7 ± 26.6 | 0.65 |
us-CRP, mg/dL | 6.13 ± 15.9 | 6.2 ± 9.96 | 3.14 ± 3.73 | 10.5 ± 21.3 | 0.89 |
Leukocytes, /mm3 | 8689 ± 3189 | 8978 ± 4480 | 8446 ± 2921 | 7620 ± 2118 | 0.61 |
Platelets, x103/mm3 | 239 ± 101 | 218 ± 511 | 236 ± 606 | 226 ± 596 | 0.61 |
BNP, pg/mL | 120 ± 191 | 163 ± 222 | 169 ± 252 | 437 ± 573 | 0.21 |
Fibrinogen, mg/dL | 392 ± 88 | 343 ± 86 | 354 ± 86 | 344 ± 83 | 0.12 |
Creatinin, mg/dL | 1.07 ± 0.33 | 1.16 ± 0.18 | 1.06 ± 0.28 | 1.24 ± 0.68 | 0.044 |
BNP: type-B natriuretic peptide; CKMB: creatine kinase, MB fraction; HbA1c: glycated hemoglobin; HOMA: Homeostasis Model Assessment; HDL: high-density lipoprotein; LDL: low-density lipoprotein; us-CRP: ultrasensitive C-reactive protein; TnI: cardiac troponin I.