Figure 4.
Effects of [Ca2+]o on dynamics of force (a and c) and Ca2+ transients (b and d). Pooled data for time to peak (a and b) and time from peak to 50% relaxation (c and d) of Ca2+ transients and twitch force (n = 6 in each group). In both groups, time to peak force increased as [Ca2+]o was increased without changes in time to peak Ca2+ transients. In mutant muscles, relaxation of force was significantly prolonged at [Ca2+]o > 6.0 mM, whereas decay of Ca2+ transients was significantly accelerated. *P < 0.05.