Figure 4.
Cell-cell adhesion assay. Following PDT, the cells were incubated for periods of 6, 12, 24 and 48 h. At the end of these periods the cultures were analyzed by fluorescence microscopy, counting the number of cells adhered to the monolayer. After 24 h, the difference in the adhesion ability in the treatment groups, compared with the control, was significant (***P<0.001). When comparing the photosensitizers ZnPc and AlPcS4, there was no significant difference. PDT, photodynamic therapy; AlPcS4, aluminum phthalocyanine tetrasulfonated; ZnPc, zinc phthalocyanine.