Figure 2.

Selection of LMIs with higher weighting factors. Weighting factors (or loading) for individual LMIs were calculated using principal component analysis-discriminant analysis. LMIs showing a higher weighting factor in each independent analysis were selected for further identification and validation. There was a slight mass shifting in repeated matrix-assisted laser desorption/ionization-time-of-flight analyses. LMIs with 184.05 and 496.30 m/z showed strong and constant discriminating power for ovarian cancer screening. LMI, low-mass ion.