Figure 5. Distribution of bimodal genes in hierarchical clusters after primary analysis.

Hierarchical clustering of processed (A) neutrophil and (B) T lymphocyte data after data exclusion by standard deviation cutoff and normalization by standardization of genes resulted in cell clusters defined by shared gene expression patterns. Genes that were multimodal before primary analysis are indicated. Bimodal genes are indicated by B-M (indicating that one peak consists only of cells with missing values for the gene) or B-L (indicating that one peak consists both of missing values and of cells with low expression). Unimodal genes are indicated by U, and trimodal genes by T. Dendrograms for columns are not shown.