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. 2014 Jun 20;11(9):886–892. doi: 10.7150/ijms.9338

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Effect of PDBu on SK opener-induced relaxations of uterine arteries from pregnant sheep. Uterine arteries were isolated from pregnant sheep and incubated under 21% O₂ or 10.5% O₂ for 48 h. SK opener NS309 -induced relaxations of uterine arteries under normoxic (panel A) and hypoxic (panel B) treatment were determined in uterine arteries pre-contracted with norepinephrine (1 μM), in the absence (control) or presence of 1 μM PDBu. Data are means ± SEM of tissues from 5-8 animals in each group.