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. 2014 May 8;165(3):1328–1343. doi: 10.1104/pp.114.238378

Figure 10.

Figure 10.

Schematic working model of ESCRT-III function on the PVC/MVB. Four marker proteins, aleurain-GFP, GFP-VIT1, LRR84A-GFP, and EMP12-GFP, reach the LV via the PVC/MVB from secretory or endocytic pathways. The ESCRT-III complex and its regulator SKD1 function on the PVC/MVB to sequester specific membrane cargoes and generate luminal vesicles. ER and TGN are omitted from the model for clarity. CW, Cell wall; LPVC, late prevacuolar compartment. [See online article for color version of this figure.]