Table I.
Correlation between BANCR expression and clinicopathological parameters of colorectal cancer patients.
| BANCR expression | ||||||
|---|---|---|---|---|---|---|
|
|
||||||
| Characteristic | n | High (n=18) | % | Low (n=42) | % | P-value |
| Age, years (mean ± SEM) | 60 | 60.4±17.3 | 64.6±14.5 | 0.333 | ||
| Gender | 0.253 | |||||
| Male | 35 | 13 | 37.1 | 22 | 62.9 | |
| Female | 25 | 5 | 20.0 | 20 | 80.0 | |
| Tumour size, cm | 0.253 | |||||
| <4 | 25 | 5 | 20.0 | 20 | 80.0 | |
| ≥4 | 35 | 13 | 37.1 | 22 | 62.9 | |
| Location | 0.167 | |||||
| Colon | 32 | 7 | 21.9 | 25 | 78.1 | |
| Rectum | 28 | 11 | 39.3 | 17 | 60.7 | |
| Histological grade | 0.207 | |||||
| Well/moderately | 44 | 11 | 25.0 | 33 | 75.0 | |
| Poorly/other | 16 | 7 | 43.8 | 9 | 56.3 | |
| Depth of invasion | 0.192 | |||||
| T1, T2 | 15 | 2 | 13.3 | 13 | 86.7 | |
| T3, T4 | 45 | 16 | 35.6 | 29 | 64.4 | |
| Lymph node metastasis | 0.010b | |||||
| Absent | 33 | 4 | 12.1 | 26 | 78.8 | |
| Present | 27 | 14 | 51.9 | 16 | 59.3 | |
| Serum CEA value, μg/l | 0.085 | |||||
| <5 | 35 | 7 | 20.0 | 28 | 80.0 | |
| ≥5 | 25 | 11 | 44.0 | 14 | 56.0 | |
| Tumour stagea | <0.001b | |||||
| I, II | 28 | 2 | 7.0 | 26 | 93.0 | |
| III, IV | 32 | 16 | 50.0 | 16 | 50.0 | |
a
Tumour stage was obtained according to the tumour, node, metastasis criteria (National Comprehensive Cancer Network, 2012).
b
P<0.05 vs. present and III, IV.
BANCR, BRAF-activated long non-coding RNA; CEA, carcinoembryonic antigen; SEM, standard error of the mean.