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STAT3 expression in untreated B cells or those treated with JSI124, and the analysis of tumor function inhibition. (A) Normal mouse-derived B cells were treated with JSI124 or co-cultured with 4T1 cells, and STAT3 expression was analyzed using western blot analysis. (B) B cells were injected into 4T1-bearing mice and tumor growth was monitored. STAT, signal transducer and activator of transcription; P-, phosphorylated; PBS, phosphate-buffered saline.
