Table V.
Association of the Axin2 SNP genotypes (GG or non-GG) with the clinical characteristics.
| Genotype | Cancer aggressiveness, n (%) | Gleason score, n (%) | PSA level at diagnosis | Age in years at diagnosis | Smoking status, n (%) | Drinking status, n (%) | Hypertension, n (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|
|
|
|||||||||
| Localized | Advanced | 2–6 | 7 | 8–10 | Never | Ever | Never | Ever | No | Yes | |||
| Total n | 35 | 68 | 23 | 20 | 42 | 189 | 203 | 167 | 36 | 186 | 17 | 56 | 147 |
| GG | 24 (68.6) | 37 (54.4) | 15 (65.2) | 13 (65.0) | 21 (50.0) | 48.3 (n=91) | 71.1 (n=100) | 83 (49.7) | 17 (47.2) | 91 (48.9) | 9 (52.9) | 23 (41.1) | 77 (52.4) |
| non-GG | 11 (31.4) | 31 (45.6) | 8 (34.8) | 7 (35.0) | 21 (50.0) | 18.6 (n=98) | 70.5 (n=103) | 84 (50.3) | 19 (52.8) | 95 (51.1) | 8 (47.1) | 33 (58.9) | 70 (47.6) |
| P-value | 0.166 | 0.370 | <0.001 | 0.647 | 0.787 | 0.751 | 0.150 | ||||||
SNP, single nucleotide polymorphism; PSA, prostate-specific antigen.