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. 2014 May 27;8(2):891–897. doi: 10.3892/ol.2014.2184

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Copyright © 2014, Spandidos Publications

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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Inhibition of MACC1 attenuates the migration and invasion of OVCAR3 cells. (A) Cell migration and invasion were observed using Transwell chambers. The cells were fixed with cold methanol and then stained with crystal violet (magnification, ×100). (B) Wound-healing assay. Images were captured at 0 and 24 h. The migration capacity was significantly decreased in the MACC1-siRNA-transfected group compared with the control groups (magnification, ×100). MACC1, metastasis-associated in colon cancer 1; NC, negative control; siRNA, small interfering RNA.