Figure 4.

MACC1 suppression inhibits the in vitro angiogenic capabilities of ovarian cancer cells. Capillary-like tubes were observed and images were captured. Silencing MACC1 inhibited human umbilical venous endothelial cell (HUVEC) tube formation. The number of tubes formed per field was counted in five random fields for the blank control, NC and MACC1-knockdown groups (magnification, ×100). Data are presented as the mean ± standard deviation from three independent experiments. MACC1, metastasis-associated in colon cancer 1; NC, negative control; siRNA, small interfering RNA.