Table 3.
Crude rate and relative risk of KR due to primary OA in 153,795 Norwegian men
| No. of participants | Person-years | No. of knee replacements | KRs per 10,000 person-years (crude rate) | Multivariate adjusted RR* (95% CI) | |
|---|---|---|---|---|---|
|
Body Mass Index, kg/m
2
|
|
||||
| <23.3 |
38,967 |
470,734 |
32 |
0.7 |
1 |
| 23.4-25.1 |
38,099 |
460,094 |
79 |
1.7 |
2.35 (1.55-3.54) |
| 25.2-27.2 |
38,918 |
469,847 |
93 |
2.0 |
2.58 (1.73-3.87) |
| > = 27.3 |
37,807 |
455,912 |
226 |
5.0 |
6.16 (4.23-8.95) |
| P (test for trend) |
|
|
|
|
<0.0001 |
|
Physical activity at work
|
|
||||
| Sedentary |
58,430 |
705,549 |
114 |
1.6 |
1 |
| Moderate |
43,757 |
528,129 |
132 |
2.5 |
1.51 (1.18-1.95) |
| Intermediate |
32,304 |
389,973 |
90 |
2.3 |
1.64 (1.24-2.17) |
| Intensive |
19,118 |
230,737 |
94 |
4.1 |
2.41 (1.83-3.18) |
| P (test for trend) |
|
|
|
|
<0.0001 |
|
Physical activity at leisure
|
|
||||
| Sedentary |
29,620 |
357,537 |
80 |
2.2 |
1 |
| Moderate |
80,762 |
974,895 |
245 |
2.5 |
1.02 (0.79-1.31) |
| Intermediate |
38,982 |
470,681 |
98 |
2.1 |
0.96 (0.71-1.30) |
| Intensive |
4,350 |
52,544 |
6 |
1.1 |
0.84 (0.36-1.94) |
| P (test for trend) |
|
|
|
|
0.668 |
|
Height
|
|
||||
| < 174 |
44,106 |
532,390 |
126 |
2.4 |
1 |
| 175-178 |
36,438 |
439,896 |
111 |
2.5 |
1.38 (1.06-1.78) |
| 179-182 |
35,289 |
426,040 |
91 |
2.1 |
1.33 (1.01-1.76) |
| > = 183 |
37,960 |
458,286 |
102 |
2.2 |
1.64 (1.25-2.15) |
| P (test for trend) |
|
|
|
|
0.001 |
|
Smoking
|
|
||||
| Never smoker |
46,945 |
566,770 |
126 |
2.2 |
1 |
| Former smoker |
41,371 |
499,259 |
161 |
3.2 |
1.00 (0.79-1.27) |
| Smoker |
65,479 |
790,606 |
143 |
1.8 |
0.82 (0.64-1.04) |
| P (test for trend) | 0.092 | ||||
*Adjusted for age at screening, height, smoking habits, BMI and physical activity at work, and at leisure time.