. 2014 Jan 3;466(10):1963–1985. doi: 10.1007/s00424-013-1421-y

Table 3.

Results of nonlinear regression analyses for the simulated time-dependent endolymphatic THO concentration change in the experimental models SV/SM, ST/SM and SV + ST/SM

	SV/SM	ST/SM	SV + ST/SM	In vivo SV + ST/SM (Konishi et al. [44])
P′ (min⁻¹)	0.691	0.499	0.869	0.85
P″ (min⁻¹)	0.938	0.940	0.898	0.9
α (min⁻¹)	0.504	0.435	0.549	0.4

The variables P′ (rate constant of THO exchange between the perilymph and endolymph), P″ (rate constant of endolymphatic water extrusion) and α (time constant) are given in Eq. (2)