Alignment of the PAS kinase PAS domain and kinase domain amino acid sequences from various model organisms. The amino acid sequence from S. cerevisiae Psk1 (ScPsk1), S. cerevisiae Psk2 (ScPsk2), D. melanogaster (DmPASK), G. gallus (GgPASK), B. taurus (BtPASK), H. sapiens (HsPASK), P. troglodytes (PtPASK), R. norvegicus (RtPASK), D. rerio (DrPASK), and M. musculus (MmPASK) were obtained from GenBank and aligned using the Clustal Omega and Jalview software (49,50). The semiconserved phosphorylation loop threonine is indicated by an asterisk. No discernable PASK homologs were found for the model organisms A. thaliana, O. sativa, C. elegans, or A. mellifera. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]