Figure 10.

The network of protein interaction, phenotype and disease class based on disease-related cliques. The red node represents known disease proteins, and the yellow nodes are predicted disease proteins. The blue dot line denotes non-interaction relationship between nodes in the “Interaction” subgraphs. The disease proteins are connected by same phenotypes and disease classes in the “Phenotype” and “Disease class” subgraphs, respectively. Gray lines of varying thickness indicate the degree of disease phenotypic and the class similarity between disease genes, respectively.