Table 3.
Comparison of variant carriers between patients and controls
| SNP- |
Allele frequency controls (n = 150) |
Allele frequency patients (n = 156) |
χ2 | P value | Corrected P value1 | OR | 95%CI | ||
| gene name | Major | Minor | Major | Minor | lower-upper | ||||
| rs1227756 | 0.49 | 0.51 | 0.44 | 0.56 | 0.02 | 0.88 | 0.93 | 1.04 | 0.54-2.03 |
| COL13A1 | |||||||||
| rs12137855 | 0.77 | 0.23 | 0.73 | 0.27 | 0.41 | 0.51 | 0.62 | 1.20 | 0.68-2.12 |
| LYPLAL1 | |||||||||
| rs1390096 | 0.68 | 0.32 | 0.66 | 0.34 | 0.007 | 0.93 | 0.93 | 0.97 | 0.55-1.70 |
| HS3ST1-HSP | |||||||||
| rs1421201 | 0.88 | 0.12 | 0.85 | 0.15 | 1.60 | 0.20 | 0.36 | 1.55 | 0.78-3.10 |
| intronic | |||||||||
| rs2073080 | 0.81 | 0.19 | 0.69 | 0.31 | 8.42 | 0.003 | 0.02 | 2.36 | 1.31-4.22 |
| PARVB | |||||||||
| rs2143571 | 0.80 | 0.20 | 0.69 | 0.31 | 6.25 | 0.01 | 0.05 | 2.07 | 1.16-3.69 |
| SAMM50 | |||||||||
| rs2228603 | 0.97 | 0.03 | 0.92 | 0.08 | 4.09 | 0.04 | 0.12 | 3.29 | 1.10-9.84 |
| NCAN | |||||||||
| rs2499604 | 0.53 | 0.47 | 0.60 | 0.40 | 3.76 | 0.05 | 0.13 | 1.92 | 0.98-3.75 |
| intronic | |||||||||
| rs2645424 | 0.5 | 0.50 | 0.56 | 0.44 | 1.21 | 0.27 | 0.40 | 0.69 | 0.36-1.32 |
| FDFT1 | |||||||||
| rs2710833 | 0.60 | 0.40 | 0.66 | 0.34 | 3.09 | 0.07 | 0.17 | 0.56 | 0.30-1.07 |
| intronic | |||||||||
| rs2854117 | 0.58 | 0.42 | 0.55 | 0.45 | 4.24 | 0.03 | 0.12 | 1.83 | 1.02-3.28 |
| APOC3 | |||||||||
| rs343062 | 0.55 | 0.45 | 0.52 | 0.48 | 1.96 | 0.16 | 0.32 | 1.53 | 0.84-2.80 |
| intronic | |||||||||
| rs4240624 | 0.94 | 0.06 | 0.91 | 0.09 | 1.21 | 0.27 | 0.40 | 1.56 | 0.69-3.52 |
| PPP1R3B | |||||||||
| rs6487679 | 0.89 | 0.11 | 0.75 | 0.25 | 9.65 | 0.001 | 0.01 | 2.81 | 1.44-5.48 |
| PZP | |||||||||
| rs6591182 | 0.63 | 0.37 | 0.59 | 0.41 | 0.99 | 0.31 | 0.44 | 1.39 | 0.72-2.67 |
| intronic | |||||||||
| rs738409 | 0.92 | 0.08 | 0.60 | 0.40 | 46.37 | 0.0001 | 0.001 | 12.66 | 5.45-29.38 |
| PNPLA3 | |||||||||
| rs780094 | 0.76 | 0.24 | 0.74 | 0.26 | 0.48 | 0.48 | 0.62 | 1.22 | 0.69-2.15 |
| GCKR | |||||||||
| rs887304 | 0.82 | 0.18 | 0.83 | 0.17 | 0.19 | 0.65 | 0.73 | 0.87 | 0.47-1.59 |
| EFCAB4B | |||||||||
| rs11206226 | 1.00 | 0.00 | 1.00 | 0.00 | - | - | - | - | |
| YIPF1 | |||||||||
1
Benjamini and Hochberg false discovery rate correction was applied to the “P value”. PNPLA3: Patatin-like phospholipase domain containing 3; NCAN: Neurocan; GCKR: Glucokinase regulatory protein; LYPLAL1: Lysophospholipase-like protein 1; PPP1R3B: Protein phosphatase 1, regulatory subunit 3B; PZP: Pregnancy zone protein.