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. 2014 Jun 27;6(6):435–442. doi: 10.4254/wjh.v6.i6.435

Table 4.

Significant single nucleotide polymorphisms associated with higher odds of body mass index, triglycerides and alanine transaminase based on clinical characteristics

Variable SNP-gene OR P value 95%CI
lower-upper
BMI (obese and non-obese) rs2073080-PARVB 1.81 0.0470 1.00-3.25
BMI (obese and non-obese) rs343062-intronic 2.25 0.0100 1.21-4.21
BMI (obese and non-obese) rs6591182-intronic 2.05 0.0340 1.05-4.00
TG (abnormal and normal) rs2854117-APOC3 2.31 0.0040 1.29-4.13
TG (abnormal and normal) rs738409-PNPLA3 1.94 0.0170 1.12-3.37
ALT (abnormal and normal) rs2073080-PARVB 1.92 0.0200 1.10-3.36
ALT (abnormal and normal) rs2143571-SAMM50 1.77 0.0200 1.10-3.36
ALT(abnormal and normal) rs2228603-NCAN 3.23 0.0180 1.22-1.37
ALT (abnormal and normal) rs6487679-PZP 1.92 0.0300 0.05-3.51
ALT (abnormal and normal) rs738409-PNPLA3 5.07 0.0001 0.03-10.92

BMI: Body mass index; TG: Triglycerides; ALT: Alanine transaminase; SNP: Single nucleotide polymorphisms.