Table 1.
Study | Number of patients | Age (yr) | Alcohol consumption | Exclusion criteria |
Rosenberg et al[24] (2004) | 64 | 18-74 | No data | Any disorder associated with extrahepatic fibrosis; cardiovascular disease or cancer; advanced cirrhosis; regular consumption of aspirin; hepatocellular carcinoma or drug-induced liver disease |
Calès et al[20] (2005) | 95 | 18-74 | ≥ 50 g/d for the previous 5 yr (mean: 94 g/d ± 50) | Other causes of LD or complicated cirrhosis or received antifibrotic treatment within the previous 6 mo |
Naveau et al[4] (2005) | 221 | 47 (SE = 0.7) | at least 50 g/d over the previous year | Concomitant liver disease, HIV antibodies, immune-suppression, hepatic surface antigen, antibodies to HCV, associated severe diseases |
Naveau et al[22] (2009) | 218 | 47.1 (SE = 0.7) | ≥ 50 g/d during the preceding y (mean 146 g/d, SE = 80 g/d for 17 yr) | Concomitant liver disease, human immunodeficiency virus antibodies, immunosupression |
Poynard et al[23] (2012) | 218 | 47 (SD = 10.3) | No data | HIV co-infection |
HCV: Hepatitis C virus; LD: Liver disease; HIV: Human immunodeficiency virus.