TABLE 6.
Facilitate ICSSa | No Change or Depress ICSS | |
---|---|---|
Maintain self-administrationb | Amphetamine | Haloperidol |
Phenmetrazine | Clonidine | |
MDMA | Zolpidem | |
Cocaine | Baclofen | |
Methylphenidate | MPEP | |
MDPV | WIN55212-2 | |
Apomorphine | ||
Methadone | ||
Morphine | ||
Nalbuphine | ||
Nicotine | ||
Varenicline | ||
Scopolamine | ||
Midazolam | ||
Chlordiazepoxide | ||
Diazepam | ||
Pentobarbital | ||
Phenobarbital | ||
Toluene | ||
Ethanol | ||
MK-801 | ||
Phencyclidine | ||
Ketamine | ||
Δ9-THC | ||
Testosterone | ||
Tripelennamine | ||
Fail to maintain Self-administration | Caffeine | Fenfluramine |
Citalopram | ||
Atomoxetine/nisoxetine | ||
Imipramine/desipramine | ||
Chlorpromazine | ||
TFMPP | ||
SNC80 | ||
U69593 | ||
Naloxone | ||
URB597 |
ICSS references are cited in section III.
Drug self-administration references are as follows: baclofen (Griffiths et al., 1991), MDPV (Watterson et al., 2014), MK-801 (Koek et al., 1988), MPEP (van der Kam et al., 2009), TFMPP (Fantegrossi et al., 2005), SNC80 (Negus et al., 1998), toluene (Blokhina et al., 2004), U69593 (Negus et al., 2008), URB597 (Justinova et al., 2008), WIN55212-2 (Fattore et al., 2001). For all other drugs, results are taken from (O'Connor et al., 2011; Horton et al., 2013).