Table 3.
Functional Connectivity in Regions of the dMPFC Subsystem Predicts Social Functioning and Empathy/Perspective-Taking
| ROI-to-ROI Correlation Predicting (→) Social Variable | R2 [95% CI] | b [95% CI] | t | p |
|---|---|---|---|---|
| lTPJ-LTC → SAS | .159 [.021, .364] | −11.44 [−20.21, −4.46] | 2.50 | .018 |
| dMPFC-TempP → IRI-PT | .126 [.004, .390] | 7.86 [.09, 13.36] | 2.18 | .036 |
| dMPFC-TempP → IRI-FS | .152 [.002, .451] | 11.15 [.34, 21.53] | 2.43 | .021 |
| LTC-TempP → IRI-PD | .150 [.007, .366] | 9.72 [2.66, 17.68] | 2.41 | .022 |
Note. lTPJ=left temporo-parietal junction, LTC=lateral temporal cortex, dMPFC=dorsal medial prefrontal cortex, TempP=temporal pole, SAS=Social Adjustment Scale – Self-Report, IRI-PT=Perspective-Taking, IRI-FS=Fantasy Scale, IRI-PD=Personal Distress.