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. 2014 Jul 4;5:117. doi: 10.3389/fneur.2014.00117

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Copyright © 2014 Mackey, Stinear, Stott and Byblow.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Three participants’ images from structural and functional MRI. From left to right: anatomical T1-weighted image; fMRI contrast results thresholded to z > 2.3: both hands active condition; left hand active condition; right hand active condition. From top to bottom: participant no. 19 with right hemiplegia and high hand function (93% MUUL) showing normal contralateral (M1/S1, PMd, PMv) and medial (SMA) activation; Participant no. 20 with right hemiplegia and average hand function (79% MUUL) showing a shift in fMRI activation lateralized to CL hemisphere for the affected right hand condition: participant no. 13 with left hemiplegia and poor hand function (41% MUUL) showing less activation than Participant no. 19 but with some remaining contralateral organization.