. Author manuscript; available in PMC: 2015 May 1.

Published in final edited form as: Trends Endocrinol Metab. 2014 Apr 18;25(5):274–282. doi: 10.1016/j.tem.2014.03.006

Table 1. GPCRs in autophagy regulation.

GPCR	Effect on Autophagy	REF

Amino acid sensing receptors:	Suppress	[11]
T1R1-T1R3 (Heterodimeric taste receptors)		[12]
MGL-1, MGL-2 (C. elegans metabotropic glutamate receptor homologs)

Muscarinic receptors:	Promote	[12-21]
GAR-3 acetylcholine receptors in C. elegans Acetylcholine receptors in rat H9C2 cardiomyoblasts		[25]

GLP-1 receptor	Promote	[29-31]

β-adrenergic receptors: Both β₁ and β₂ adrenergic receptors	Promote	[16, 18-19]

Purinergic receptors: P2Y₁₃ ADP receptor	Promote	[36]