Table 1.
Results of independent SNPs reaching genome wide significance (P<5 × 10−8) in the ProtecT GWAS
Loci | SNP | Chromosome | Position | Alleles | β a | SEb | ORc | P-value | EAFd | RSQRe |
---|---|---|---|---|---|---|---|---|---|---|
10q11.23 | rs10993994 | 10 | 51219502 | T/C | 0.33 | 0.06 | 1.39 | 1.58 × 10−09 | 0.5983 | 0.9793 |
17q24.3 | rs7222314 | 17 | 66616533 | A/G | 0.32 | 0.06 | 1.38 | 8.59 × 10−09 | 0.4772 | 0.9295 |
19q13.33 | rs1058205 | 19 | 56055210 | T/C | 0.40 | 0.07 | 1.49 | 4.63 × 10−08 | 0.1828 | 1 |
Correlation coefficient
Standard Error
Effect estimate (odds ratio)
Effect Allele Frequency
Imputation accuracy