Table 5.
Multivariate regression analysis assessing the correlation between HbA1c and circulating progenitor cells levels, after adjustment for other cardiovascular risk factors than diabetes
| Variable |
CD45dimCD34+KDR+ levels |
CD45dimCD34+KDR+CXCR4+ levels |
CD133+KDR+ levels |
CD133+KDR+CXCR4+ levels |
||||
|---|---|---|---|---|---|---|---|---|
| Standard coefficient (ß) | p | Standard coefficient (ß) | p | Standard coefficient (ß) | p | Standard coefficient (ß) | p | |
| HbA1c |
-0.308 |
0.019 |
-0.260 |
0.031 |
-0.342 |
0.009 |
-0.416 |
0.001 |
| Age |
-0.188 |
0.217 |
-0.107 |
0.482 |
-0.254 |
0.090 |
-0.052 |
0.720 |
| Gender |
0.208 |
0.067 |
0.207 |
0.119 |
0.044 |
0.740 |
0.158 |
0.233 |
| Hypertension |
-0.071 |
0.597 |
-0.075 |
0.579 |
0.025 |
0.855 |
-0.015 |
0.905 |
| LDL-cholesterol |
-0.057 |
0.683 |
-0.047 |
0.727 |
-0.176 |
0.202 |
-0.148 |
0.267 |
| Family history of CAD |
-0.129 |
0.361 |
-0.170 |
0.202 |
0.081 |
0.560 |
0.078 |
0.563 |
| Smoking habits |
0.003 |
0.985 |
-0.204 |
0.188 |
-0.086 |
0.563 |
-0.133 |
0.369 |
| Physical inactivity |
-0.203 |
0.139 |
-0.080 |
0.556 |
-0.057 |
0.657 |
-0.167 |
0.180 |
| Adjusted R2 |
0.264 |
… |
0.256 |
… |
0.246 |
… |
0.247 |
… |
| Significance (ANOVA) | … | 0.032 | … | 0.040 | … | 0.046 | … | 0.033 |
CAD, coronary artery disease; HbA1c, hemoglobin A1c; LDL, low density lipoprotein.