Table 3.
Conditions | Clonogenicity (%) |
---|---|
No additions | 100 ± 4 |
Bafilomycin | 96 ± 5 |
Ru360 | 91 ± 4 |
BPD PDT | 85 ± 6 |
Baf + BPD PDT | 19 ± 3* |
Ru360 + Baf + BPD PDT | 46 ± 3*† |
Conditions are specified in the legend to Table 1. Bafilomycin B1 (Baf, 50 nM) or Ru360 (10 μM) were present during the 60 min BPD loading incubation. Cultures were then resuspended in fresh medium, irradiated and colony formation evaluated. Data represent average ± SD for triplicate samples.
Statistically different from controls;
statistically different from result obtained with reverse order of irradiation (p < 0.05). .